PURPOSE:This study aimed to evaluate the safety, tolerability and pharmacokinetics of the combination of oral vinorelbine with erlotinib using the conventional (CSV) and metronomic (MSV) dosing schedules in patients with advanced non-small cell lung cancer (NSCLC).METHODS:This was an open-label, multiple dose-escalation phase I study.An alternating
We describe baseline characteristics, time to treatment initiation and interim patient outcomes at a decentralized, outpatient treatment site for rifampicin-resistant TB (RR-TB).Prospective observational cohort study of RR-TB patients from March 2013 until December 2014.Study subjects were followed until completion of the intensive phase Planters o
Nowadays, the Internet of Things (IoT) has become a rapid development; it can be employed by cyber threats in IoT devices.A correct system to recognize malicious attacks at IoT platforms became of major importance Adhesion Promoter to minimize security threats in IoT devices.Botnet attacks have more severe and common attacks and it is threaten IoT
Forage fish support the largest fisheries INDESIT DD60C2CX.1 60 cm Electric Ceramic Cooker - Mirror in the world and play a vital role in marine food webs by transferring energy from plankton to consumers within higher trophic levels.Growing commercial demand for these species and concern for the impact of over harvest on predator populations has d
Kathleen M Antony,1,2 Judy Levison,1 Melissa A Suter,1 Susan Raine,1 Grace Chiudzu,3 Henry Phiri,3 Joseph Sclafani,1,3,4 Michael Belfort,1 Peter Kazembe,4 Kjersti M Aagaard1 1Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX, USA; 2Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Universit